Welcome

Hey there! I’m Blake, a computational research scientist with a penchant for tea. I have a background in computational physical chemistry with additional postdoctoral experience in cancer systems biology and nano-bioengineering. My expertise includes molecular simulation and encompasses molecular dynamics, Monte Carlo, and free energy simulation methods. In addition to my molecular simulation skills, I have experience with differential equation-based reaction-diffusion and reaction network models of chemical and biological systems, such as cellular signaling processes; my skillset in this domain also includes parameter estimation using stochastic optimization and Bayesian inference methods, as well as model selection, information theoretics, and dynamical model analysis. I’m also proficient with Linux/UNIX systems, Bash scripting, and Python programming (with a background in C++), and I have extensive experience utilizing high-performance computing environments.

Want learn more? Check out the About Me section for a deeper dive into my academic and professional journey.

Interested in my skills and experience - let’s connect! I am currently exploring new career opportunities that could leverage my experience in research and skills in scientific computing, and I’d be happy to discuss how I can contribute to your team. See the Contact page for ways to get in touch.

Most Recent PhD

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Recent Work

Academic Publications/Preprints

  1. Journal Article (2025) Chen Xie, Peiyuan Kang, Jonghae Youn, Blake A. Wilson, Tingting Zhang, Lokesh Basvarajappa, Qingxiao Wang, Moon Kim, Lei Li, Kenneth Hoyt, Jaona Harifidy Randrianalisoa, and Zhenpeng Qin, Mechanism of Amplified Photoacoustic Effect for Silica-Coated Spherical Gold Nanoparticles, Nano Lett. https://doi.org/10.1021/acs.nanolett.4c05558
  2. Journal Article (2024) Oscar O. Ortega, Mustafa Ozen, Blake A. Wilson, James C. Pino, Michael W. Irvin, Geena V. Ildefonso, Shawn P. Garbett, and Carlos F. Lopez, Signal execution modes emerge in biochemical reaction networks calibrated to experimental data, iScience. https://doi.org/10.1016/j.isci.2024.109989
  3. Journal Article (2024) Chen Xie, Blake A. Wilson, and Zhenpeng Qin, Regulating nanoscale directional heat transfer with Janus nanopartilces, Nanoscale Adv. https://doi.org/10.1039/D3NA00781B
  4. Journal Article: (2024) Hejian Xiong*, Blake A. Wilson*, Xiaoqian Ge*, Xiaofei Gao, Qi Cai, Xueqi Xu, Robert Bachoo, and Zhenpeng Qin, Glioblastoma Margin as a Diffusion Barrier Revealed by Photoactivation of Plasmonic Nanovesicles, Nano Lett. (*=co-first authors) https://doi.org/10.1021/acs.nanolett.3c04101

Visit PUBLICATIONS to view a full list of publications.

Latest Blog Posts

(11/15/2024) Antibody-Drug Conjugates (ADCs) Part 1 - What are ADCs? | Exploring Precision Cancer Therapies series
Graphical Abstract

(10/30/2024) Radioligand Therapy (RLT) Part 3 - Modeling how clearance, binding, and uptake affect tumor targeting and off-target emissions using a semi-mechanistic PK/PD approach | Exploring Precision Cancer Therapies series
Graphical Abstract

(10/17/2024) Radioligand Therapy (RLT) Part 2 - Modeling how radionuclide half-life affects tumor targeting and off-target emissions using a semi-mechanistic PK/PD approach | Exploring Precision Cancer Therapies series
Graphical Abstract

Software Releases